Later during development, individual TCR revision ( editing ) and change its antigenic specificity.
2.
This happens so that the full repertoire of antigenic specificities of lymphocytes is continuously represented throughout the body.
3.
O-antigens ( the outer carbohydrates ) are the most variable portion of the LPS molecule, imparting the antigenic specificity.
4.
Scientists initially thought that it was an antigenic specificity of HBV, but they soon found that it was a protein from another disease altogether.
5.
During class switching, the constant region of the immunoglobulin heavy chain changes but the variable regions, and therefore antigenic specificity, stay the same.
6.
These retain their antigenic specificity and can be used to produce antitoxins and, in the case of diphtheria and tetanus toxoids, are used as vaccines.
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