| 1. | The equilibrium of the reaction favors the formation of barbituric acid.
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| 2. | Barbiturase is very specific to barbituric acid and will not react with derivatives.
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| 3. | Urea, malonate, and cyanuric acid inhibit the hydrolysis of barbituric acid.
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| 4. | In addition, barbituric acid inhibits multiple enzymes that are involved in de novo pyrimidine synthesis.
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| 5. | Barbiturates are derivatives of barbituric acid.
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| 6. | It is a common reagent for organic synthesis used, for example, as a precursor for barbituric acid.
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| 7. | Which is a multicomponent reaction of N, N'- dimethyl-barbituric acid, benzaldehyde and ethyl vinyl ether.
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| 8. | In 1903, he published observations that barbital ( then known as diethyl-barbituric acid ) has sedative properties in humans.
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| 9. | In 1912, Bayer introduced another barbituric acid derivative, phenobarbital, under the trade name Luminal, as a sedative-hypnotic.
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| 10. | The species is prepared by addition of ammonia to o-phthalonitrile to give the diiminoisoindoline, which in turn condenses with barbituric acid.
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