These cells are derived from the dental sac or follicle.
2.
The " dental sac or follicle " gives rise to three important entities : cementoblasts, osteoblasts, and fibroblasts.
3.
It is believed that either 1 ) HERS becomes interrupted; 2 ) infiltrating dental sac cells receive a reciprocal inductive signal from the dentin; or 3 ) HERS cells transform into cementoblasts.