From 1909 MacCallum investigated a unique tetanic condition called gastric tetany, in which parathyroid glands are normal.
2.
In 1909 he discovered that a disease gastric tetany was not due to parathyroid functions, but because of blockage of the stomach-intestine connection called pylorus.
3.
He found in dogs that under gastric tetany, gastric hydrochloric acid was lost, and the chlorine in the blood plasma was reduced causing severe electrolyte imbalance.