Some, such as ano-vaginal and perianal fistulas are chronic conditions, and in many cases will not heal without surgical intervention.
2.
On July 28, 2016 " The Lancet " published the 24-Week Results of the Phase 3 ADMIRE-CD Trial Investigating Cx601 in the Treatment of Complex Perianal Fistulas in Patients with Crohn s Disease.
3.
TiGenix has completed, and received positive data in, a single pivotal Phase III trial in Europe of its most advanced product candidate Cx601, a potential first-in-class injectable allogeneic stem cell therapy indicated for the treatment of complex perianal fistulas in patients suffering from Crohn's disease.
4.
In addition to hip dysplasia, Leonbergers can inherit and / or develop heart problems, Inherited Leonberger Paralysis / Polyneuropathy ( ILPN ), osteosarcoma, hemangiosarcoma, Osteochondrosis Dissecans, allergies, digestive disorders, cataracts, entropion / ectropion eyelids, progressive retinal atrophy ( PRA ), perianal fistulas, and thyroid disorders.
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