| 11. | Cortisol and ACTH are much more easily measured in blood than CRF.
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| 12. | In these cases, ACTH levels remain low and no hyperpigmentation develops.
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| 13. | An ACTH-secreting corticotrophic pituitary adenoma should be removed after diagnosis.
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| 14. | ACTH stimulation testing is not recommended to confirm the diagnosis.
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| 15. | Adrenocorticotropic hormone ( ACTH ) stimulates the adrenal cortex to release corticosteroids.
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| 16. | ACTH causes the adrenal glands to then release cortisol into the blood.
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| 17. | ACTH levels are however low, and CBG levels increase.
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| 18. | ACTH induces the release of corticosteriods and aldosterone from the adrenal gland.
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| 19. | Equivocal levels of ACTH indicate ectopic or Paraneoplastic Cushing's Syndrome.
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| 20. | Emicerfont blocks the CRF 1 receptor, and so reduces ACTH release.
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