These enzymes share a 3-layer alpha-beta-alpha structure, and play important roles in arginine / agmatine metabolism, the urea cycle, histidine degradation, and other pathways.
12.
Agmatine has been shown to exert modulatory action at multiple molecular targets, notably : neurotransmitter systems, ion channels, nitric oxide ( NO ) synthesis and polyamine metabolism and this provides bases for further research into potential applications.
13.
When neural tissue is incubated in agmatine and an external stimulus is applied, only cells with open channels will be filled with agmatine, allowing identification of which cells are sensitive to that stimuli and the degree to which they opened their cationic channels during the stimulation period.
14.
When neural tissue is incubated in agmatine and an external stimulus is applied, only cells with open channels will be filled with agmatine, allowing identification of which cells are sensitive to that stimuli and the degree to which they opened their cationic channels during the stimulation period.
15.
In step three, the primary amino group of agmatine attacks the C2 carbon of the p-C34 intermediate to release ?-Pi and form agm 2 C . TiaS also autophosphorylates its Thr18 with the ?-phosphate of ATP, releasing AMP and ?-Pi.
16.
Both the " gabD " and " gabT " genes were shown, in various experiments, to be induced by metabolites such as agmatine and lysine that would fit with either of the two activities just mentioned for the products of " gabD " / " gabT ".
