| 11. | The aldosterone system is directly targeted by spironolactone, an aldosterone antagonist.
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| 12. | Aldosterone synthase is a member of the cytochrome P450 superfamily of enzymes.
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| 13. | Aldosterone can be inhibited by antialdosteronic drugs such as spironolactone and eplerenone.
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| 14. | Aldosterone, on the other hand, has differing levels.
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| 15. | ACTH induces the release of corticosteriods and aldosterone from the adrenal gland.
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| 16. | Aldosterone activates sodium channels that result in sodium resorption from the urine.
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| 17. | This causes the release of aldosterone into the blood.
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| 18. | When aldosterone is present, more sodium is reabsorbed and more potassium secreted.
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| 19. | In human adrenocortical cells, cinobufagin inhibits the secretion of aldosterone and cortisol.
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| 20. | Adrenal hormones such as cortisol and aldosterone also increase.
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