| 11. | In normal stem cells, the activity of alkaline phosphatase activity is lowered upon differentiation.
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| 12. | Alkaline phosphatase ( ALP ) is an enzyme in the cells lining the Paget's disease.
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| 13. | The first manifestation of Paget's disease is usually an elevated alkaline phosphatase in the blood.
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| 14. | It can also cause elevations in hepatic enzymes such as gamma-glutamyl transferase and alkaline phosphatase.
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| 15. | An example of phosphorylating enzyme is found in alkaline phosphatase in its periplasmic region of its membrane.
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| 16. | Modest rises in the serum alkaline phosphatase, aspartate transaminase, and amylase may also be seen.
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| 17. | The pacient also has abnormal liver test results, such as high GGT and alkaline phosphatase levels.
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| 18. | Female homozygotes had a decreased respiratory quotient, increased circulating alkaline phosphatase level and increased leukocyte cell number.
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| 19. | Homozygous mutant animals displayed hyperactivity and brain dysmorphology, while males also had decreased circulating alkaline phosphatase levels.
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| 20. | Moreover, it can increase alkaline phosphatase activities of mesoblasts, enhance cell proliferation and promote cell adhesion.
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