The dogs had a version of Leber congenital amaurosis, an untreatable condition that causes near total blindness in infancy.
12.
His symptoms began at age 28 with a sudden transient visual loss ( amaurosis fugax ) after the funeral of a friend.
13.
Upon awakening from the coma, some experience amaurosis fugax : a " dark " and " fleeting " unilateral temporary blindness.
14.
In 2008, three groups reported positive results of clinical trials using adeno-associated virus for Leber's Congenital Amaurosis.
15.
Mutations in this gene have been associated with Leber's congenital amaurosis type 2 ( LCA2 ) and retinitis pigmentosa ( RP ).
16.
Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2.
17.
In 1857 Derby had amaurosis ( today, some historians think he had a brain tumor ), which prevented him from reading or writing.
18.
NEI-funded scientists discovered that treating patients with gene therapy for Leber congenital amaurosis ( LCA ) may improve eyesight and sensitivity of the retina.
19.
Several clinical trials have already reported positive results using rAAV to treat Leber's congenital amaurosis, showing that the therapy was both safe and effective.
20.
Leber was the first to describe what is now known as Leber's congenital amaurosis in 1869 and Leber's hereditary optic neuropathy in 1871.
