Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome ( TDO ) and amelogenesis imperfecta with taurodontism.
12.
A mutation in FAM20A was reported to be associated with amelogenesis imperfecta, an inherited enamel defect, and gingival hyperplasia syndrome.
13.
About 5 % of amelogenesis imperfecta cases are caused by mutations in the AMELX gene and are inherited in an X-linked pattern.
14.
Mutations in the AMELX gene can result in amelogenesis imperfecta, which refers to the collection of enamel defects resulting from either genetic or environmental causes.
15.
The presence of this hair texture type is a defining characteristic between a diagnosis of "'TDO "'verses amelogenesis imperfecta with hypomaturation.
16.
People afflicted with amelogenesis imperfecta have teeth with abnormal color : yellow, brown or grey; this disorder can afflict any number of teeth of both dentitions.
17.
There are some physical symptoms that have been associated with KTS . The most prominent symptom is amelogenesis imperfecta which gives the teeth a stained brown-yellow color.
18.
Amelogenesis imperfecta, an abnormal formation of the enamel or external layer of the crown of the tooth, may also be present where the tooth enamel may be thin or absent.
19.
Furthermore, individuals with the disorders of orofacial complex such as Amelogenesis imperfecta, Dentinogenesis imperfecta, Cleft lip / palate, oral cancer and a like, are also considered as special health care need patients.
20.
There are several clinical subsets of amelogenesis imperfecta, but common to TDO is the hypoplastic-hypomaturation subtype; the hypomaturation-hyoplastic is less common in individuals with "'TDO " '.
