| 11. | LRRK2 is also a substrate for chaperone-mediated autophagy.
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| 12. | GATA4 is regulated through the autophagy-lysosome pathway in eukaryotic cells.
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| 13. | Noncovalent interactions are important for its cargo targeting functions in selective autophagy.
|
| 14. | In fact an overabundance of APOL1 within a cell results in autophagy.
|
| 15. | ATG16L1 is a component of a large protein complex essential for autophagy.
|
| 16. | Atg32 silencing stops recruitment of autophagy machinery and mitochondrial degradation.
|
| 17. | Hypoxia, in turn, drives oxidative stress and autophagy.
|
| 18. | Strong induction of apoptosis and autophagy has also been seen.
|
| 19. | Moreover, mTORC2 activity has been implicated in the regulation of autophagy.
|
| 20. | Tumor cells are killed viva autophagy, rather than apoptosis.
|
