The formation of the urethane is particularly valuable since it works with carboxylic acids which fail to undergo the Schmidt reaction, and is believed to involve transfer of the azido group to the carboxylic acid.
12.
In this technique 3'- azido-2', 3'- deoxythymidine ( Zidovudine, AZT ) is first phosphorylated to AZT 5'- monophosphate ( AZTMP ) by TK1 in the sample.
13.
The hydroxyl group is replaced in a Mitsunobu reaction by an azide group with diphenylphosphoryl azide in "'7 "'and acid hydrolysis yields the azido aldehyde "'8 " '.
14.
Initially, the value of the method developed by Evans and coworkers was proved by successfully converting the resulting alpha-hydroxy ester into the corresponding methyl ester, free acid, Weinreb amide and alpha-azido ester, without any racemization, as shown in Figure 18.
15.
Much like the " Altered States of America " album, both discs contain hidden tracks : " Azido Phencyclidine Electrophoresis " on disc one and " Submachine Drum ( Agoraphonic Nosecandy mix ) " on disc two, both of which are accessible by rewinding the first track.
