In vitro studies have shown that AMG 706 inhibits human endothelial cell proliferation induced by VEGF, but not by basic fibroblast growth factor, as well as vascular permeability induced by VEGF in mice.
12.
He points out that other substances which repair neurons _ such as nerve growth factor and basic fibroblast growth factor _ have been shown to repair axons, the fibers that transmit nerve signals.
13.
Acidic and basic fibroblast growth factor, neurotrophin 3, transforming growth factor beta 1, transforming growth factor beta 2, nerve growth factor, brain derived neurotrophic factor can be given as examples for such growth factors.
14.
The Mountain View, California-based company said Wednesday the U . S . Patent and Trademark Office issued it a patent covering the method of making human basic fibroblast growth factor by recombinant DNA techniques.
15.
It has been shown to directly interact with the human securin and proto-oncogene, PTTG1, thus facilitating its nuclear translocation and the subsequent transcriptional activation of basic fibroblast growth factor ( bFGF ) by PTTG1.
16.
Endostatin is a broad-spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor ( bFGF / FGF-2 ) and vascular endothelial growth factor ( VEGF ).
17.
As well as blocking a protein involved in blood vessel growth called vascular endothelial growth factor, the new drug also interferes with two other blood vessel growth factors _ basic fibroblast growth factor and platelet-derived growth factor.
18.
There are five growth factors that have been shown to be significantly upregulated and active during tendon healing : insulin-like growth factor 1 ( IGF-I ), platelet-derived growth factor ( PDGF ), vascular endothelial growth factor ( VEGF ), basic fibroblast growth factor ( bFGF ), and transforming growth factor beta ( TGF-? ).
