Benzonitrile, the original product of Letts, has multiple uses as a versatile reagent and as a solvent.
12.
Palladium chloride is insoluble in most organic solvents, but it forms soluble monomeric units with acetonitrile and benzonitrile:
13.
Nitrotoluene, methyl benzoate and benzoic acid are nitrated by prolonged exposure over a few days . Benzonitrile does not react.
14.
They have similar boiling points ( about 10 C apart ), But benzonitrile will hydrolyse into benzamide and then benzoic acid.
15.
As an example, bis ( triphenylphosphine ) palladium ( II ) dichloride may be prepared from palladium ( II ) chloride by reacting it with triphenylphosphine in benzonitrile:
16.
His earlier work included an investigation of succinic acid, and the preparation of phenyl cyanide ( better known as benzonitrile ), the simplest nitrile of the aromatic series.
17.
"' Benzonitrile "'is the chemical compound with the formula C 6 H 5 CN, abbreviated PhCN . This aromatic organic compound is a colorless liquid with a sweet almond odour.
18.
Today, I saw a ( fairly contrived ) mass spectrum for benzonitrile, with only a small peak at 77 normally associated with the breakdown of benzene; instead it had a peak at 76.
19.
The main use of benzonitrile appears to be as a powerful solvent in the pharmaceutical industry, and as an intermediate in the production of a triazine called " benzoguanamine ", which is similar to melamine.
20.
Benzonitrile is a precursor in the synthesis of Fadrozole, an aromatase inhibitor used in the treatment of breast cancer . 4-( trifluoromethyl ) benzonitrile, produced by the Nickel catalyzed cyanation of 4-chlorobenzotrifluoride is a precursor for the antidepressant Fluvoxamine.
