The N and Q teloblasts contribute two blast cells per segment, one making up the anterior half of the segment, the second making up the posterior half of the segment.
12.
During development, the N and Q bandlets, which eventually have 64 blast cells each, slide past the O, P, and M bandlet, which only have 32 cells.
13.
Many of the immature blast cells in acute myeloid leukemia have a higher loss of function and thus, a higher inability to carry out normal functions than those more developed immature myeloblast cells in chronic myeloid leukemia ( O Donnell et al . 2012 ).
14.
The hemangioblast theory, which posits that the RBCs and ECs derive from a common progenitor cell, was developed as researchers observed that receptor knockout mice, such as blast cells derived from embryonic stem ( ES ) cells displayed common gene expression of both hematopoietic and endothelial precursors.
15.
First, the percentage of undifferentiated progenitor cells, blast cells, is always less than 20 %, and there is considerably more dysplasia, defined as cytoplasmic and nuclear morphologic changes in erythroid, granulocytic and megakaryocytic precursors, than what is usually seen in cases of AML . These changes reflect delayed apoptosis or a failure of programmed cell death.
