Nobody knows where bryostatin-1 comes from, whether from a stringy little sea creature known as " Bugula neritina " or from bacteria that live in the creature's stringy gut.
12.
Saturn tries to end Bugula but fails eventually Bugula decides to surrender to him by putting Saturn's dart on his leg however the dart has alcohol and Bugula is arrested and loses custody of his child.
13.
Saturn tries to end Bugula but fails eventually Bugula decides to surrender to him by putting Saturn's dart on his leg however the dart has alcohol and Bugula is arrested and loses custody of his child.
14.
Saturn tries to end Bugula but fails eventually Bugula decides to surrender to him by putting Saturn's dart on his leg however the dart has alcohol and Bugula is arrested and loses custody of his child.
15.
In granting a temporary restraining order sought by scientists and south Florida environmental groups, Judge Henry Kennedy specifically cited a court affidavit in which one of the plaintiffs noted that Bugula neritina is a relative of the newly discovered Florida bryozoans.
16.
But Bugula neritina's distant kinship to several species of bryozoans discovered in sand the corps was dredging from the ocean floor in the renourishment project was a factor in a federal judge's decision to temporarily halt the Fort Pierce project.
17.
In 1968 GSML provided the first specimens of the bryozoan " Bugula neritina " used by the National Cancer Institute ( NCI ) to develop the bryostatin family of drugs used for treatment of cancer, HIV, Alzheimer s disease and strokes.
18.
"' Bryostatins "'are a group of macrolide lactones first isolated in the 1960s by George Pettit from extracts of a species of bryozoan, " Bugula neritina " based on research from samples originally provided by Jack Rudloe to Jonathan L . Hartwell s anticancer drug discovery group at the National Cancer Institute ( NCI ).
19.
Rudloe was involved in early efforts to establish the now successful jellyfish export industry on the East Coast of the US . In 1968 he provided the first specimens of the bryozoan " Bugula neritina " used by the National Cancer Institute ( NCI ) to develop the bryostatin family of drugs used for treatment of cancer, HIV, Alzheimer s disease and strokes.
20.
The former, ?-conotoxin, is used to relieve severe and chronic pain, Other natural products derived from marine animals and under investigation as possible therapies include the antitumour agents discodermolide ( from the sponge " Discodermia dissoluta " ), eleutherobin ( from the coral " Erythropodium caribaeorum " ), and the bryostatins ( from the bryozoan " Bugula neritina " ).
