Dock7 and other DOCK family proteins differ from other GEFs in that they do not possess the canonical structure of tandem C-termini, however, these regions in Dock7 are poorly characterised thus far and no such features have been identified.
12.
The statement calls on the church to explore " new canonical structures " to facilitate lay involvement in the church, saying that the current structures, such as diocesan pastoral councils representing laypeople and presbyteral councils representing priests, " in many cases . . . have atrophied into uselessness, whether through benign neglect or deliberate suppression ."
13.
In a letter in September 2013, Archbishop Vincent Nichols, President of the Catholic Bishops'Conference of England and Wales, explained that, through the canonical structure of the ordinariate, " Anglicans who wish to enter the full communion of the Catholic Church, bringing with them some of the traditions and beauty of the Anglican heritage in which they were nurtured, may do so ."
14.
The HIF1A polypeptide also contains a nuclear localization signal motif, two transactivating domains CTAD and NTAD, and an intervening inhibitory domain ( ID ) that can repress the transcriptional activities of CTAD and NTAD . There are a total of three HIF1A isoforms formed by alternative splicing, however isoform1 has been chosen as the canonical structure, and is the most extensively studied isoform in structure and function.
