| 11. | Thereafter, the carboxylic acid can successfully attach to the backbone by esterification.
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| 12. | However, carboxylic acids tend to be less reactive than esters as electrophiles.
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| 13. | They are used to prepare mixed carboxylic acid anhydrides used in peptide synthesis.
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| 14. | Carboxylic acids react with Grignard reagents and organolithiums to form ketones.
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| 15. | The remaining acidic carboxylic acid group can then again be titrated with base.
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| 16. | Derivatives of metalla " dithia " carboxylic acids are also known.
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| 17. | The carboxylate ion on acidification will give its corresponding carboxylic acid.
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| 18. | Cellulose and hemicellulose is degraded to aliphatic carboxylic acid soaps and hemicellulose fragments.
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| 19. | Additionally, carboxylic acids can be esterified with alcohols, to produce esters.
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| 20. | Primary alcohols will be oxidised to aldehydes and not carboxylic acids.
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