In skeletal muscle dystrophy, mitochondrial dysfunction gives rise to an amplification of stress-induced cytosolic calcium signals and an amplification of stress-induced cascading process that involves several pathways and is not clearly understood, increased oxidative stress within the cell damages the sarcolemma and eventually results in the death of the cell.
12.
Philips Cascade process is the second most-used, used in 10 trains with a total capacity of 36.16 MMTPA . The Shell DMR process has been used in three trains with total capacity of 13.9 MMTPA; and, finally, the Linde / Statoil process is used in the Snohvit 4.2 MMTPA single train.
13.
According to his Oxford University profile, Anderson's research has " a particular focus on the total synthesis of biologically active molecules, and the development of new reactions including cascade processes . . . Within the theme of reaction development, we have particular interests in the use of metal-mediated reactions to rapidly construct complex functional molecules, and in new applications of organosilicon chemistry ."
