| 11. | The gene product is also associated with centrosome maturation.
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| 12. | Centrosomes are the major microtubule organizing center ( MTOC ) in mammalian cells.
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| 13. | The centrosome cycle consists of four phases that are synchronized to cell cycle.
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| 14. | Centrosome duplication is heavily regulated by cell cycle controls.
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| 15. | The role of centrosomes in tumor progression is unclear.
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| 16. | Then NPM is released from binding to an unduplicated centrosome, thereby triggering duplication.
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| 17. | Plant cells lack centrosomes as microtubule organizing centers.
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| 18. | Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
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| 19. | Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
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| 20. | Centrosome duplication and maturation regulated by Plk1 occurs from late S phase to prophase.
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