Nventa originally advanced HspE7 as a single-agent therapy into multiple Phase 2 clinical trials with positive results, including trials in cervical dysplasia and recurrent respiratory papillomatosis ( RRP ).
12.
Since then, over 1, 100 women have been screened, 80 have gone through curative treatment for cervical dysplasia ( LEEP ), and 19 have had hysterectomies performed on them.
13.
Fewer HPV infections mean fewer complications from the virus and less time and money spent on the detection, work-up, and treatment of cervical cancer and its precursor, cervical dysplasia.
14.
In 1963, Stern published what is widely recognized as the first case report linking a specific virus ( herpes simplex ) to a specific cancer ( contraceptive pill with cervical dysplasia.
15.
Certain HPV types, in particular types 16 and 18, can also lead to progression from a benign wart to low or high-grade cervical dysplasia, which are reversible forms of precancerous lesions.
16.
The candidate is being developed with a Toll-like receptor 3 ( cervical intraepithelial neoplasia ( also known as cervical dysplasia or CIN ), genital warts, cervical cancer, and head and neck cancers.
17.
Six months later, Dr . Olenski treats Pepper Steiger ( Nicky Whelan ) for stage 2 cervical dysplasia and incorrectly diagnosis Susan Kennedy ( Jackie Woodburne ) with the menopause, when she is really suffering from Multiple sclerosis.
18.
It is estimated that nearly 10 million women are diagnosed with some form of cervical dysplasia each year in major global markets in the U . S ., EU and Japan, many of whom could benefit from a non-surgical treatment.
19.
Supracervical hysterectomy does not eliminate the possibility of having cervical cancer since the cervix itself is left intact and may be contraindicated in women with increased risk of this cancer, regular pap smears to check for cervical dysplasia or cancer are still needed.
20.
Nventa has indicated that it is currently working with the U . S . Food and Drug Administration ( FDA ) to finalize the trial design for a Phase 2 clinical study for HspE7 in patients with high grade cervical dysplasia ( CIN 2 / 3 ).
