Pfizer, in a prepared statement released after repeated calls from the Globe, had this to say about the mouse study : " It is not known whether these results are applicable to humans, since pregabalin is not a chemical mutagen and not genotoxic in pre-clinical studies.
12.
One interesting result from the Ames test is that the dose response curve using varying concentrations of chemical is almost always linear, However some proposed that organisms can tolerate low level of mutagens due to protective mechanisms such as DNA repair, and threshold may exist for certain chemical mutagens.
13.
In addition to studying the effect of radiation for SLT, Russell et al . were also interested in studying the effect of chemical mutagens such as procarbazine and ethylnitrosourea for SLT . At that time, procarbazine was the most potent chemical mutagen known to cause a significant spermatogonial mutagenesis in an SLT, although at a rate one-third of that of X-rays.
14.
In addition to studying the effect of radiation for SLT, Russell et al . were also interested in studying the effect of chemical mutagens such as procarbazine and ethylnitrosourea for SLT . At that time, procarbazine was the most potent chemical mutagen known to cause a significant spermatogonial mutagenesis in an SLT, although at a rate one-third of that of X-rays.
15.
In fact regulatory requirements mean most GM food receive far more testing for health effects then foods produced via other techniques e . g . modern plant breeding ( which nowadays often includes a large variety of things like chemical mutagens and radiation, modern plant breeding is definitely quite different from what we've been doing for thousands of years, unlike what some people seem to think ).
