The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid.
12.
A test performed after the mixture is incubated for 1 to 2 hours at 37�C will show significant prolongation over the clotting time obtained after immediate mixing.
13.
Other features of fat malabsorption may also occur such as reduced bone density, difficulty with vision under low light levels, bleeding, bruising and slow blood clotting times.
14.
The clotting time is based on a relative scale and requires a baseline value for a point of comparison due to inconsistencies between the source and formulation of the activator being used.
15.
High doses of vitamin E may produce headaches, tiredness, double vision, and diarrhea in humans and doses higher than 800 mg may increase blood clotting time, especially for people on blood thinners.
16.
Five minutes after the bolus dose has been administered, an activating clotting time ( ACT ) should be performed and an additional bolus of 0.3 mg / kg should be given if needed.
17.
If the mixing test indicates an inhibitor, diagnosis of a lupus anticoagulant is then confirmed with phospholipid-sensitive functional clotting testing, such as the dilute Russell's viper venom time, or the Kaolin clotting time.
18.
Clotting time measurements can be affected by other drugs that such as Warfarin, aprotinin and GPIIb / IIIa inhibitors and may also be affected by physical perturbations to the body such as hypothermia, hypervolemia or hypovolemia.
19.
Even if that should happen in Bradley's case _ which would mean that he'd have to have his clotting time monitored and perhaps modify his diet _ Salem still didn't think that should disqualify him from serving as president.
20.
Furthermore, in 97 % of all cases the blood clotting time was prolonged ( more than 12 minutes ), 41 % had bleeding ( usually from the gums ), 32 % had local blistering and 9 % had necrosis.