Formation of pores by cholesterol-dependent cytolysins ( CDC ) requires the presence of cholesterol in the target cell.
12.
Cytolysins form pores in the cytoplasmic membrane that allows for the passage of ions and other molecules into the cell.
13.
Structural studies reveal that MACPF domains are related to cholesterol-dependent cytolysins ( CDCs ), a family of pore forming toxins previously thought to only exist in bacteria.
14.
Nelfinavir and simple derivatives have been found to inhibit the production of the virulence factor streptolysin S, a cytolysin produced by the human pathogen " Streptococcus pyogenes ".
15.
Tomita et al . 2004 purified pleurotolysin, a sphingomyelin-specific two-component cytolysin from the basidiocarps of " Pleurotus ostreatus " and studied pore-formation.
16.
In the second step, cytolysins adhere to target cell membranes by matching the " " receptors are proteins, but they can be other molecules as well, such as lipids or sugars.
17.
In addition, Sheldon showed that the bacterium Trueperella pyogenes becomes a pathogen in the uterus by secreting a cholesterol-dependent cytolysin that damages stromal cells, once the epithelium is damaged after parturition.
18.
Nelfinavir and these related molecules did not exhibit detectable antibiotic activity, but did also inhibit the production of other biologically active molecules, including plantazolicin ( antibiotic ), listeriolysin S ( cytolysin ), and clostridiolysin S ( cytolysin ), by other bacteria.
19.
Nelfinavir and these related molecules did not exhibit detectable antibiotic activity, but did also inhibit the production of other biologically active molecules, including plantazolicin ( antibiotic ), listeriolysin S ( cytolysin ), and clostridiolysin S ( cytolysin ), by other bacteria.
