Tracheal cytotoxin itself is able to reproduce paralysis of the ciliary escalator, inhibition of DNA synthesis in epithelial cells and ultimately killing of the same.
12.
This investigational therapeutic approach of targeting the cytotoxin to hypoxic zones in tumors may cause less broad systemic toxicity that is seen with untargeted cytotoxic chemotherapies.
13.
With a molecular mass of 308 kDa, it is usually described as a potent enterotoxin, but it also has some activity as a cytotoxin.
14.
Microparticles obstruct arterioles that supply small nests of cells throughout the body and, together with cytotoxins, damage organs and tissues and temporarily disturb organ function.
15.
Toxin B ( TcdB ) is a cytotoxin that has a molecular weight of 270 kDa and an isoelectric point, pl, of 4.1.
16.
Unlike most other " Bordetella " toxins, tracheal cytotoxin is expressed constitutively, being a normal product of the breakdown of the bacterial cell wall.
17.
Its venom contains powerful neurotoxins and cytotoxins, including mucopolysaccharides, hyaluronidases, phospholipases, serotonins, histamines, enzyme inhibitors, and proteins such as neurotoxic peptides.
18.
In this study with a prevalence of positive cytotoxin assays of 14 %, the positive predictive value was 18 % and the negative predictive value was 94 %.
19.
The active ingredient in G-202 is a chemotherapeutic agent derived from thapsigargin, a plant-based cytotoxin that kills by disrupting the calcium balance in cancer cells.
20.
Some kinds of blue-green algae create neurotoxins, hepatoxins, cytotoxins or endotoxins that can cause serious and sometimes fatal neurological, liver and digestive diseases in humans.
