| 11. | However, how sulfatide buildup causes demyelination and neural degeneration is still mostly unknown.
 
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 | 12. | Once demyelination of the pons has begun, there is no cure or specific treatment.
 
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 | 13. | Anti-MOG mediated demyelination was shown to behave similar to NMO in animal models,
 
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 | 14. | Electromyographic studies and noninflammatory axonopathy without demyelination.
 
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 | 15. | This demyelination is shown to cause mitochondrial dysfunction in axons, leading to their degeneration.
 
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 | 16. | In these cases it is only possible to speak about tumefactive demyelination ( TD ).
 
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 | 17. | Unexplained, uniform demyelination of white matter can indicate acute onset Grinker's myelinopathy.
 
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 | 18. | Fibers were observed some of which showed a sign of primary ( segmental ) demyelination.
 
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 | 19. | There is a combination of demyelination and axonal damage, and autonomic neurones are all affected.
 
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 | 20. | This leads to cerebral inflammatory demyelination caused by the myelin destabilization that occurs in these patients.
 
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