Some evidence suggest the presence of metabolic pathways for the sequential oxidation and glucuronidation of PST in vitro, both being the initial detoxication reactions for the excretion of these toxins in humans.
12.
The C-hydroxylated metabolites may be considered as the detoxication products, while the benzenediazonium ion ( BDI ) formed by microsome-catalyzed enzymatic splitting of the azo group of Sudan I, reacts with DNA " in vitro > ".
