The cause of this might be detrusor overactivity, in which the bladder muscle ( the detrusor ) contracts unexpectedly during bladder filling.
12.
Incontinence will occur if the bladder muscles suddenly contract ( detrusor muscle ) or muscles surrounding the urethra suddenly relax ( sphincter muscles ).
13.
Inhibitory signals from the brain fail to suppress the overactive detrusor muscle and it contracts inappropriately during the bladder-filling phase, causing involuntary voiding.
14.
"' Pseudodyssynergia "'( or detrusor sphincter pseudodyssynergia ) is an urological condition involving contraction of the female external sphincter during voiding.
15.
One possibility is that the voluntary relaxation of the muscles of the pelvic floor causes a sufficient downward tug on the detrusor muscle to initiate its contraction.
16.
Other experiments done by Malysz et al . have looked into ethanol effects on voltage-gated calcium channels on detrusor smooth muscle cells in guinea pigs.
17.
Van Koeveringe, G . A ., K . L . Rademakers, et al . ( 2014 ) . " Detrusor underactivity : Pathophysiological considerations, models and proposals for future research.
18.
In an overactive bladder, peaks of increased pressure by the detrusor muscle are recorded during the filling phase, indicating periods of involuntary muscle contraction at a time when a normal muscle remains relaxed.
19.
It is also a common treatment used among spinal cord injury patients who are unable or unwilling to use intermittent catheterization to empty the bladder, and cannot otherwise void due to detrusor sphincter dyssynergia.
20.
A typical classification categorizes DU into neurogenic vs . myogenic etiologies, however this classification fails to consider the impact of adaptive sensory and motor responses on detrusor voiding function in response to physiologic stressors.
