The modern era began with an industrial poison, dinitrophenol, used by as many as 100, 000 people in 1933 to control their weight.
12.
In the presence of acetic anhydride, the enzyme is inactivated, unable to catalyze the hydrolysis reaction 2, 4-dinitrophenyl propionate to dinitrophenol.
13.
During World War I the Russians gave their soldiers 2, 4-dinitrophenol, a chemical found in explosives, to keep them warm in winter.
14.
The drug 2, 4-dinitrophenol, which also acts as a chemical uncoupler similarly to UCP1, was used for weight loss in the 1930s.
15.
Are there any drugs other than DNP ( 2, 4-dinitrophenol ) which are known to increase metabolic uncoupling for the purpose of weight loss?
16.
A small percentage of the intermediate loses the chloride to become the product ( 2, 4-dinitrophenol ), while the rest return to the reactant.
17.
Duchaine is also credited with introducing 2, 4-dinitrophenol ( DNP ) into bodybuilding through an interview on one of ten cassettes included with bodybuilding magazine Muscle Media 2000.
18.
Till that time Wolman s formulation famously known as Wolman Salts contained dinitrophenol, a chemical manufactured by Hicksons, UK . No copper was used in Wolman Salts.
19.
The IUPAC name is 2-( butan-2-yl )-4, 6-dinitrophenol and its molecular formula is C 10 H 12 N 2 O 5.
20.
In the first experiment, two narcotics, tricaine methanesulfonate and 1-octanol, and two uncouplers of oxidative phosphorylation, pentachlorophenol and 2, 4-dinitrophenol, were used.
