In the case of an allyl alcohol compound with a proximate carbonyl functional group, the epoxide can undergo a ring-expansion reaction to form a dioxolane.
12.
Substituting formaldehyde by other aldehydes or ketones results in a 2-substituted 1, 3-dioxolane ( yield : 70 85 %, catalyst : tetraethylammonium bromide ).
13.
In this case, the use of trifluoroperacetic acid derived from hydrogen peroxide, which therefore presumably contained traces of water, gave mostly a hemiacetal rather than the closed-ring dioxolane.
14.
This is because if TNP-ATP is acidified under mild conditions, it results in the opening of the dioxolane ring attached to the 2-oxygen, leaving a 3 O-TNP derivative as the only product.
15.
It is also an heterocyclic compound with a five-membered ring, and can be seen as a derivative of dioxolane, specifically "'4-ethyl-1, 3-dioxolan-2-one " '.
16.
In the case of neosporol, a Prilezhaev reaction with trifluoroperacetic acid is used to convert a suitable allyl alcohol precursor to an epoxide, which then undergoes a ring-expansion reaction with a proximate carbonyl functional group to form the dioxolane ring.
17.
TADDOLs ( tetraaryl-1, 3-dioxolane-4, 5-dimethanols ), which are derived from chiral tartaric acid, are a class of diol ligands often used to bind titanium, but have been adopted for zinc addition chemistry.
18.
The selectivity and speed of dimerization can be increased by adding a catalyst, such as platinum, platinum-palladium or iodine with sulfolan; however, 2-methyl-1, 3-dioxolane is formed as a side product in the last case.
19.
It is also an heterocyclic compound with a five-membered ring containing two oxygen atoms, and can be viewed as a derivative of dioxolane, namely " "'cis "-4, 5-dimethyl-1, 3-dioxolan-2-one " '.
20.
Lipid nanoparticles ( LNPs ) are being considered for delivering siRNA to silence AR . The most effective LNP to be found in vivo contains an ionizable cationic lipid 2, 2-dilinoleyl-4-( 2-dimethylaminoethyl )-[ 1, 3 ]-dioxolane ( DLin-KC2-DMA ).
