This dithiol pair attacks the periplasmic N-terminal disulfide bridge at C103 and C109 ( C1 and C2, respectively ) which transfers electrons to DsbC and other protein electron acceptors as noted above.
12.
A further example of an acetal formed from a cyclic ketone, except with a dithiol, is the spiro compound spirapril, which has a five-membered ring formed from 1, 2-ethanedithiol.
13.
The parent compound ( dithiol ) is known as are a bunch of salts and simple alkyl ( including dialkylsulfonium on one of the sides ) . talk ) 20 : 37, 2 February 2012 ( UTC)
14.
Another selenium-bearing enzyme in some plants and in animals ( thioredoxin reductase ) generates reduced thioredoxin, a dithiol that serves as an electron source for peroxidases and also the important reducing enzyme ribonucleotide reductase that makes DNA precursors from RNA precursors.
15.
A related selenium-containing enzyme in some plants and in animals ( thioredoxin reductase ) generates reduced thioredoxin, a dithiol that serves as an electron source for peroxidases and also the important reducing enzyme ribonucleotide reductase that makes DNA precursors from RNA precursors.
16.
The biologically active form of oxytocin, commonly measured by HPLC techniques, is also known as the octapeptide " oxytocin disulfide " ( oxidized form ), but oxytocin also exists as a reduced straight-chain ( non-cyclic ) dithiol nonapeptide called oxytoceine.
17.
In " A . aegypti " mosquitoes, RNR1 retains most of the crucial amino acid residues, including aspartate ( D64 ) and valine ( V292 or V284 ), that are necessary in allosteric regulation; proline ( P210 and P610 ), leucine ( L453 and L473 ), and methionine ( M603 ) residues that are located in the hydrophobic active site; cysteine ( C225, C436 and C451 ) residues that are involved in removal of a hydrogen atom and transfer of the radical electron at the active site; cysteine ( C225 and C436 ), asparagine ( N434 ), and glutamate ( E441 ) residues that bind the ribonucleotide substrate; tyrosine ( Y723 and Y743 ) residues that dictate the radical transfer; and cysteine ( C838 and C841 ) residues that are used in the regeneration of dithiol groups in the active site.
