Since then, the gill it innervated has become the larynx and the gill arch has become the dorsal aorta in mammals.
12.
Thus the co-expression of cell surface markers from both lineages suggests that hematopoietic stem cells differentiate from endothelial cells of the dorsal aorta in the AGM.
13.
The intersegmental arteries are a set of 30 arteries arising from the embryonic dorsal aorta, with each artery providing blood supply to one somite and its derivatives.
14.
It contains the dorsal aorta, genital ridges and mesonephros and lies between the notochord and the somatic mesoderm, extending from the umbilicus to the anterior limb bud of the embryo.
15.
For a period during embryonic development, the dorsal aorta produces hematopoietic stem cells, which will eventually colonise the liver and give rise to all mature blood lineages in the adult.
16.
During organogenesis ( around the fourth week in human embryos ), the visceral region of the mesoderm, the splanchnopleura, transforms into distinct structures consisting of the dorsal aorta, genital ridges and mesonephros.
17.
Shortly after gastrulation, cells from the dorsolateral plate, analogous to the splanchnopleura mesoderm in mammals, migrate to the midline, beneath the notochord to form the dorsal aorta, and laterally the cardinal veins and nephric ducts.
18.
The fish are pumped from the water into a slurry of ice and water, which slows them down; their dorsal aortas are severed, and they are put back in the slurry to pump out their blood.
19.
Mouse embryonic models show expression of EphA1 in mesoderm and pre-endocardial cells, later spreading up into the dorsal aorta then primary head vein, intersomitic vessels, and limb bud vasculature, as would be consistent with a role in angiogenesis.
20.
Definitive hematopoiesis then occurs later in the aorta-gonad-mesonephros ( AGM ), a region of embryonic mesoderm that develops into the ventral wall of the dorsal aorta, at E10.5 in mice and 4wpc ( 4 weeks post-conception ) in humans.
