In states of prolonged kidney failure and subsequent uremia, the high level of urea in the bloodstream leads to high levels of urea secreted by eccrine sweat glands as a component of sweat.
12.
This gene was identified by its association with ectodermal dysplasia, and specifically with hypohidrotic ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands.
13.
When all of the eccrine sweat glands are working at maximum capacity, the rate of perspiration for a human being may exceed three liters per hour, and dangerous losses of fluids and electrolytes can occur.
14.
:Sweat glands, specifically Eccrine sweat glands-note : there are more on palms than on backs of hand ( ~ 370 sweat glands per cm 2 vs . ~ 200 per cm 2 ); our article doesn't mention feet . ~ E : talk ) 21 : 59, 28 December 2013 ( UTC)
