In this mechanism, a basic sidechain of the enzyme abstracts the aldehyde proton from C 1; at the same time, the a proton is added to the oxygen of C 2, thus forming a " enediol ".
12.
Some ketoses may be accessible from similar aldoses by isomerization via an enediol intermediate; for example, on standing in aqueous base, glucose, fructose, and mannose will slowly interconvert since they share an enediol form . ( See mutarotation ).
13.
Some ketoses may be accessible from similar aldoses by isomerization via an enediol intermediate; for example, on standing in aqueous base, glucose, fructose, and mannose will slowly interconvert since they share an enediol form . ( See mutarotation ).
14.
Phosphoglucose Isomerase ( PGI ) has a very similar function to PMI, ( as it catalyzes the interconversion of Glucose 6-Phosphate and F6P ) however PGI can anomerize alpha and beta G6P, and may also catalyze the conversion of alpha M6P to beta M6P, while PMI may not anomerize M6P . It is likely the cis-enediol intermediate formed by PMI is the same intermediate formed by PGI.
