A series of toxicology tests combined with a review of other reported studies concluded that erythrosine is non-genotoxic and the above-mentioned increase in tumors is caused by a non-genotoxic mechanism.
12.
As a result of efforts begun in the 1970s, in 1990 the U . S . FDA had instituted a partial ban on erythrosine, citing research that high doses have been found to cause cancer in rats.
13.
While commonly used in many countries of the world, erythrosine is less commonly used in the United States ( the second least used after Fast Green FCF ) because Allura Red AC ( Red # 40 ) is generally used instead.
