It is also possible to make a reasonably accurate self-diagnosis at home by careful examination of the tongue and looking for the number of fungiform papillae.
12.
Fungiform papillae are present on the anterior portion of the tongue while circumvallate papillae and foliate papillae are found on the posterior portion of the tongue.
13.
The fungiform papillae are innervated by the seventh cranial nerve, more specifically via the submandibular ganglion, chorda tympani, and geniculate ganglion ascending to the solitary nucleus in the brainstem.
14.
TAS1R1 + 3 expressing cells are found in fungiform papillae at the tip and edges of the tongue and palate taste receptor cells in the roof of the mouth.
15.
TAS1R1 + 3 expressing cells are found mostly in the fungiform papillae at the tip and edges of the tongue and palate taste receptor cells in the roof of the mouth.
16.
Prior to this, A . Hoffmann had concluded, in 1875, that the dorsal center of the human tongue has practically no fungiform papillae and taste buds, and it was this finding that the diagram describes.
17.
After staining my tongue blue with vegetable dye ( it delineates the fungiforms, which stay pink, from other tongue tissue ), Bartoshuk tells me there is an area of my tongue where the fungiform papillae are missing.
18.
This condition is limited to the upper ( dorsal ) surface of the tongue, affecting some of the tiny bumps on the tongue known as the fungiform papillae, what we commonly call the " taste buds ."
19.
The cause of this heightened response is unknown, although it is thought to be related to the presence of the TAS2R38 gene, the ability to taste PTC, and, at least in part, due to an increased number of fungiform papillae.
