Human genomic libraries were screen under low-stringency conditions using probes from animal retroviruses, allowing the isolation and characterization of multiple, though defective, proviruses, that represented various families.
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A similar method can be used to titer genomic libraries made with non-viral vectors, such as plasmids and ligation of the library can be used to transform E . coli.
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The number of clones that constitute a genomic library depends on ( 1 ) the size of the genome in question and ( 2 ) the insert size tolerated by the particular cloning vector system.
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Current average ratings of the Genomic library page ( through the feedback tool ) are 2.4 out of 5 in 67 ratings in completeness; additionally, the trustworthiness of the article is given a 2.9 out of 5 in 67 ratings.
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This sequence of cDNA was used to find the remaining DNA sequences comprising the Factor IX gene by searching the DNA in the X chromosome : A genomic library from a human XXXX chromosome was prepared . . . and screen [ ed ] with a Factor IX cDNA probe.