| 11. | The deposited fibroblastic connective tissue matures by secreting ECM into the extracellular space, forming granulation tissue ( see below ).
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| 12. | Granulation tissue and new blood vessels form, and fragments of necrotic bone ( sequestra ) are separated from vital bone.
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| 13. | They form a loose aggregate of cells, interspersed with small blood vessels, known as " granulation tissue ".
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| 14. | In a rat model of free-radical scavenging property, HA has been shown to reduce damage to the granulation tissue.
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| 15. | An excess of granulation tissue ( " caro luxurians " ) is informally referred to as " proud flesh ."
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| 16. | Although inflammation is an integral part of granulation tissue formation, for normal tissue repair to proceed, inflammation needs to be moderated.
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| 17. | In chronic angular cheilitis, there may be suppuration ( pus formation ), exfoliation ( scaling ) and formation of granulation tissue.
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| 18. | If granulation tissue grows over the injured site, it can cause stenosis of the airway, after a week to a month.
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| 19. | When a cholesteatoma or granulation tissue is present in the middle ear, the degree of hearing loss and ossicular destruction is even greater.
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| 20. | Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue.
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