The toxicity was proposed to arise from the thiourea group, and similar guanidine analogues were investigated until the ultimate discovery of cimetidine.
12.
This is because guanidinium is the conjugate acid of guanidine and is called the guanidinium cation, [ CH 6 N 3 ] +.
13.
It was originally proposed that a hydrogen bond between the uracil and guanidine groups in the enol tautomer would make this the dominant form.
14.
This result was completely forgotten, as other guanidine analogs, such as the synthalins, took over and were themselves soon overshadowed by insulin.
15.
This reagent is part of the Lowry protein assay, and will also react with some nitrogen-containing compounds such as hydroxylamine and guanidine.
16.
Parsons tried to resolve GALCIT-27's stability issue with GALCIT-46, which replaced the former's ammonium nitrate with guanidine nitrate.
17.
This almost-correct molecule possesses a tricyclic guanidine group ( rings A, B & C ), along with a uracil ring ( D ).
18.
Strong and hindered non-nucleophilic guanidine bases are accessible from tetramethylurea in a simple manner, which are in contrast to the fused amidine bases DBU not alkylated.
19.
Jetex motors are powered by a solid pellet of guanidine nitrate, which burns to release a variety of gases in copious volume, leaving no solid residue or ash.
20.
With Tagamet imidazole is the the most obvious candidate for being a base with a pkB near 7, but I'm wondering why not the guanidine type residue?
