Blood-forming stem cells ( called haematopoietic stem cells ) reside in the bone marrow in very specific microenvironments.
12.
Specialised endothelial cells on the dorsal aorta of the AGM region, identified as haemogenic endothelium differentiate into haematopoietic stem cells.
13.
This would explain the increase in mesenchymal cell number, and the distinct lack of cells positive for other haematopoietic markers.
14.
Stem cell transplant is also used to treat CMML, and involves the transplantation of donor haematopoietic stem cells into the recipient.
15.
It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses.
16.
Among his contributions to medical science are investigations on the structure and embryology of the kidney, research on the haematopoietic studies in normal and pathological conditions.
17.
In contrast to the yolk sac, the extra-embryonic haematopoietic site, the number of CFU-S was much greater in the aorta gonad mesonephros region.
18.
G-CSF is a colony stimulating factor which has been shown to have minimal direct in vivo or in vitro effects on the production of other haematopoietic cell types.
19.
Experimental therapies under investigation include endothelin receptor antagonsits, tyrosine kinase inhibitors, beta-glycan peptides, halofuginone, basiliximab, alemtuzumab, abatacept and haematopoietic stem cell transplantation.
20.
IL-24 is a cytokine belonging to the T helper 2 ( Th2 ) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues.
