| 11. | They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood.
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| 12. | MHC crosslinking also activates a signaling pathway that suppresses hematopoiesis and upregulates Fas-mediated apoptosis.
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| 13. | Another complication of extramedullary hematopoiesis is poikilocytosis, or the presence of abnormally shaped red blood cells.
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| 14. | Microscopically, lymph nodes also contain foci of hematopoiesis, but these are insufficient to cause enlargement.
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| 15. | LNK functions as a regulator in signaling pathways relating to hematopoiesis, inflammation, and cell migration.
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| 16. | It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation.
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| 17. | For example, both SDS and 5q-syndrome lead to impaired hematopoiesis and a predisposition to leukemia.
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| 18. | The bone marrow stem cells give rise to cells of all hematopoietic lineages, through the process of hematopoiesis.
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| 19. | There may be evidence of extramedullary hematopoiesis ( marrow elements can be found in the spleen, liver ).
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| 20. | Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network.
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