Humans produce about 0.44 g / L hippuric acid per day in their urine, and if the person is exposed to toluene or benzoic acid, it can rise above that level.
12.
Other investigations showed specific foods, such as cranberries, prunes and plums had unusual effects on urine pH . While these foods provided an alkaline ash in the laboratory, they contain a weak organic acid, hippuric acid, which caused the urine to become more acidic instead.
13.
Hippuric acid is also known as benzoylglycine and is produced from benzoic acid in two steps : first benzoic acid is converted to benzoyl-CoA by the enzyme benzoyl-CoA synthase; then benzoyl-CoA is converted to hippuric acid by benzoyl-CoA : glycine N-acyltransferase.
14.
Hippuric acid is also known as benzoylglycine and is produced from benzoic acid in two steps : first benzoic acid is converted to benzoyl-CoA by the enzyme benzoyl-CoA synthase; then benzoyl-CoA is converted to hippuric acid by benzoyl-CoA : glycine N-acyltransferase.
15.
4-Hydroxybenzoic acid, 3, 4-dihydroxybenzoic acid ( protocatechuic acid ), 3-methoxy-4-hydroxy-hippuric acid and 3-methoxy-4-hydroxybenzoic acid ( vanillic acid ) are the main catechins metabolites found in humans after consumption of green tea infusions.
16.
In more recent years, studies have suggested the use of urinary benzylmercapturic acid as the best marker for toluene exposure, because : it is not detected in non-exposed subjects; it is more sensitive than hippuric acid at low concentrations; it is not affected by eating or drinking; it can detect toluene exposure down to approximately 15 " o "-cresol.
