In order to meet the geometric requirements for polymerization, a host-guest strategy is used by combining a host molecule and diiodobutadiyne in solution and allowing co-crystalization to occur.
12.
TLRs are a type of pattern recognition receptor ( PRR ) and recognize molecules that are broadly shared by pathogens but distinguishable from host molecules, collectively referred to as pathogen-associated molecular patterns ( PAMPs ).
13.
These cells present receptors contained on the surface or within the cell, named " pattern recognition receptors " ( PRRs ), which recognize molecules that are broadly shared by pathogens but distinguishable from host molecules, collectively referred to as pathogen-associated molecular patterns ( PAMPs ).
14.
The hydroxyl group in alcohol attacks its host molecule through intermolecular nucleophilic substitution, and at the same time, carboxylate anion, derived from 2-methyl-6-nitrobenzoic acid, acts as a deprotonation agent, promoting the progression of the esterification and producing the desired carboxylic ester.
15.
The hydroxyl group in the seco acid attacks its host molecule through intramolecular nucleophilic substitution, and at the same time, carboxylate anion, derived from 2-methyl-6-nitrobenzoic acid, acts as a deprotonation agent, promoting the progression of the cyclization and producing the desired lactone.
16.
Another assumption that is made in the determination of [ HG ] as a function of [ H ] _ o and [ G ] _ o is that by setting the initial concentration of the Guest molecules, [ G ] _ o, much greater than the initial concentration of Host molecules, [ H ] _ o; one can then say that:
17.
TLRs have been suspected of binding to host molecules including fibrinogen ( involved in blood clotting ), heat shock proteins ( HSPs ), HMGB1, extracellular matrix components and self DNA ( it is normally degraded by nucleases, but under inflammatory and autoimmune conditions it can form a complex with endogenous proteins, become resistant to these nucleases and gain access to endosomal TLRs as TLR7 or TLR9 ).
