The reaction is somewhat similar to the organophosphine as an oxide acceptor, a diazo compound as a hydrogen acceptor reagent, and a nucleophile are used to convert alcohols to esters and other applications like this.
12.
Lys264 is most likely involved in neutralizing the negative charge that develops on phosphate, and it may also serve as a general base ( hydrogen acceptor ) for the 3'OH of IP 3 . ]]
