The second generation of THC analogs features compounds derived from anandamide ( metanandamide ), aminoalkylindole ( WIN 55, 212-2 ), pyrrole, pyrazole ( SR-141716A ), and indene ( BAY 38-7271 ).
12.
Treadway, S . L ., K . S . Yanagimachi, E . Lankenau, P . A . Lessard, G . Stephanopoulos and A . J . Sinskey . 1999 . Isolation and characterization of indene bioconversion genes from Rhodococcus strain I24.
13.
"' Sporolides A and B "'are novel polycyclic macrolides from the obligate marine bacterium " Salinispora tropica " ( which is found in ocean sediment ) that are composed of a chlorinated cyclopenta [ a ] indene ring and a cyclohexenone moiety.
14.
A Reformatsky reaction with zinc amalgam and bromoacetic ester leads to carbinol ( "'5 "'), which is then dehydrated with tosic acid to indene "'6 "'. { Alternatively ths step can be performed in a Knoevenagel condensation with cyanoacetic acid, which is then further decarboxylated .}
15.
Any compound structurally derived from 1 ( 1 naphthylmethyl ) indene by substitution at the 3 position of the indene ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2 ( 4 morpholinyl ) ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.
16.
Any compound structurally derived from 1 ( 1 naphthylmethyl ) indene by substitution at the 3 position of the indene ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2 ( 4 morpholinyl ) ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.
17.
Any compound structurally derived from 1 ( 1 naphthylmethyl ) indene by substitution at the 3 position of the indene ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2 ( 4 morpholinyl ) ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.
18.
(e ) Any compound ( not being a compound for the time being specified in paragraph 1 ( ba ) of Part 1 of this Schedule ) structurally derived from 1-benzofuran, 2, 3-dihydro-1-benzofuran, 1H-indole, indoline, 1H-indene, or indane by substitution in the 6-membered ring with a 2-ethylamino substituent whether or not further substituted in the ring system to any extent with alkyl, alkoxy, halide or haloalkyl substituents and whether or not substituted in the ethylamino side-chain with one or more alkyl substituents . .
