However, in a mouse model of ovalbumin-induced allergic airway disease : "'a ) "'12-HHT and its companion cyclooxygenase metabolites, Prostaglandin E2 and Prostaglandin D2, but not 12 other lipoxygenase or cyclooxygenase metabolites showed a statistically significantly increase in bronchoalveolar lavage fluid levels after intratracheal ovalbumin challenge; "'b ) "'only 12-HHT, among the monitored BLT2 receptor-activating ligands ( i . e . LTB4, the 12 ( " S " ) stereoisomer of 12-HETE, and 15 ( " S " )-HETE ) rose to a level capable of activating BLT2 receptors; and "'c ) "'