R . P . Brown in 1984 maintained that'there is insufficient evidence to view involutional melancholy as a separate clinical entity', but at the same time that'clinical characteristics of patients with unipolar endogenous depression may be influenced by age '.
12.
Idiopathic localized involutional lipoatrophy ( ILIL ) is a rare and nosologically imprecise condition characterized by a focal loss of subcutaneous tissue on one or several sites, occurring without any significant triggering factor or auto-immune background, and regressing spontaneously within a few months
13.
By linking her depression to menopause, Mrs . Bush perpetuates a centuries-old belief that the hormonal swings that accompany this life stage can touch off what had long been called involutional ( a term referring to the body's changes at menopause ) melancholia.
14.
Mid-century, there was a consensus that the technique indeed'yields the best results in the long-lasting depressions of the change of life, the so-called " involutional melancholias ", which before this form of treatment was introduced often required years of hospitalization '.
15.
Dreyfus ( 1907 ) had challenged Kraepelin's concept of an acquired origin, maintaining it to be endogenous in origin-although'a recent statistical study of Dreyfus's old series has also shown that his conclusion that the natural history of involutional melancholia was no different from that of depression affecting younger subjects was wrong '.
