| 11. | It has been proposed that the MGAT4A isoenzyme acts as a toggle for developing of type 2 diabetes.
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| 12. | However, isoenzyme analysis reveals that it is more closely related to " Rauvolfia tetraphylla L ".
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| 13. | About 20 percent of dofetilide is metabolized in the liver via the CYP3A4 isoenzyme of the cytochrome P450 enzyme system.
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| 14. | MCPP is metabolized via the CYP2D6 isoenzyme by hydroxylation to p-hydroxy-mCPP ( OH-mCPP ).
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| 15. | Hence, this isoenzyme is an important regulator of glycolysis and additional functions in other novel roles that have recently emerged.
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| 16. | Finally C9-triazole derivatives of DANA containing an alkoxy group with a nanomolar activity against hNEU4 isoenzyme have been reported.
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| 17. | With a 500-fold selectivity for hNEU4, this is the highest reported selectivity for a hNEU isoenzyme to date.
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| 18. | An isoenzyme of glycogen phosphorylase exists in the liver sensitive to glucose concentration, as the liver acts as a glucose exporter.
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| 19. | This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration.
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| 20. | The majority of flecainide is eliminated by the kidneys, with the remainder metabolized by the cytochrome P450 2D6 isoenzyme in the liver.
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