The rates have been estimated to be approximately 1 : 100 for leiomyoma variants and 1 : 500 for leiomyosarcoma.
12.
"' Elagolix "'( phase III clinical trials for the treatment of endometriosis and uterine leiomyoma.
13.
In addition to these three classical tumors, there is an increased incidence of pheochromocytoma, esophageal leiomyoma and adrenocortical adenoma.
14.
Decreased expression of this gene in human uterine leiomyoma is found to be inversely associated with the expression of estrogen receptor alpha.
15.
This syndrome is believed to be caused by increased erythropoietin ( EPO ) production by the kidneys or by the leiomyomas themselves.
16.
Imaging modalities cannot clearly distinguish between the benign uterine leiomyoma and the malignant uterine leiomyosarcoma, however, the latter is quite rare.
17.
Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma.
18.
Uterine fibroids ( leiomyoma ) are benign tumors of the uterus that cause bleeding and pelvic pain in approximately 30 % of affected women.
19.
"' Relugolix "'( phase II clinical trials for the treatment of endometriosis, uterine leiomyoma, and prostate cancer.
20.
Other causes of gynecological bleeding need to be excluded, specifically bleeding related to pregnancy, leiomyoma, and cancer of the cervix or uterus.